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1. Depressed Mood / Inescapable Sadness : Depression may be indicated when a person feels extremely sad most of the time, nearly every day during at least a 2 week period. A depressed mood may be observed by others or expressed by the individual. In children and teens, depression also may present as an irritability.
2. Diminished Interest in Activities : Strong feelings of apathy or an inability to experience pleasure in most previously-enjoyed activities, along with a depressed or irritable mood can indicate depression. In a person who is depressed, these feelings are present most days during at least a two-week period.
3. Unexplained Weight Loss or Gain : Significant (more than 5 percent of body weight in a month) unintentional weight loss or gain, or decrease or increase in appetite nearly every day may be a sign of depression. Children who are depressed may fail to make expected growth-related weight gains.
4. Insomnia or Extreme Sleepiness : A person who is depressed may have difficulty falling asleep or may wake frequently during the night. Excessive sleepiness nearly every day for at least 2 weeks also may be a sign of depression.
5. Psychomotor Symptoms : These signs of depression are characterized by unintentional and purposeless motions, like pacing, hand-wringing or hair-twirling, or by a noticeable slowing of the thought process, emotional reactions or movement. Psychomotor agitation and psychomotor retardation observed by others nearly every day for at least 2 weeks may indicate depression.
6. Fatigue : Unexplained feelings of fatigue or a lack of energy nearly every day for a period of at least 2 weeks can be a sign of depression. Depression-related fatigue is not associated with another cause, such as an increase in physical activity or another medical condition.
7. Feelings of Guilt or Worthlessness : Excessive or inappropriate guilt or strong feelings of inadequacy can signal depression. In a person who is depressed, these feelings occur nearly every day and can be extreme enough to be delusional. Guilt is not merely self-reproach or related to being sick.
8. Diminished Ability to Concentrate : A sharp decrease in focus or concentration can be a sign of depression. People who are depressed often notice an inability to think clearly. In some cases, a lack of focus is observed by others, such as family members, friend or co-workers.
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